High-dose Daclizumab for the Treatment of Juvenile Idiopathic Arthritis–Associated Active Anterior Uveitis
نویسندگان
چکیده
منابع مشابه
The Role of Immune System in Idiopathic Anterior Uveitis
Background: Idiopathic anterior uveitis is an anterior segment inflammation in which a detailed medical history, general and ocular physical examination is not associated with any defined clinical syndrome. Alterations in immune system parameters have been reported in patients with idiopathic posterior uveitis; however no data on the role of immune system in idiopathic anterior uveitis has yet ...
متن کاملTreatment of Juvenile Idiopathic Arthritis-Associated Uveitis
Pediatric uveitis may be a serious health problem because of the lifetime burden of vision loss due to severe complications if the problem is not adequately treated. Juvenile idiopathic arthritis (JIA)-associated uveitis is characterized by insidious onset and potentially blinding chronic anterior uveitis. Periodic ophthalmologic screening is of utmost importance for early diagnosis of uveitis....
متن کاملAdalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis.
OBJECTIVE To evaluate the efficacy of adalimumab in juvenile idiopathic arthritis (JIA)-associated uveitis. METHODS Retrospective observational study of 20 patients with JIA and chronic uveitis on adalimumab treatment. The ocular inflammation and improvement was assessed according to the Standardization of Uveitis Nomenclature criteria. RESULTS At the initiation of adalimumab, the mean age ...
متن کاملJuvenile idiopathic arthritis-associated uveitis
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation. JIA-associated uveitis is a potentially sight-threatening condition and thus carries a considerable risk of morbidity. The aetiology of the condition is autoimmune in nature with the predominant involvement of CD4(+) T cells. However, ...
متن کاملJuvenile Idiopathic Arthritis associated uveitis
Systemic JIA represents 20% of all JIA cases. It is characterized by the onset of high-grade fever associated with multiple extra-articular manifestations. [2] These include maculopapular rash, generalized lymphadenopathy, hepatomegaly, splenomegaly, pericarditis, and pleuritis. Joint involvement is initially mild or absent, but becomes the more prominent feature of the disease as the patient a...
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ژورنال
عنوان ژورنال: American Journal of Ophthalmology
سال: 2009
ISSN: 0002-9394
DOI: 10.1016/j.ajo.2009.06.003